Surgical removal of a choroid plexus oncocytoma in an adult cat
2017
Cossic, B. | Silver, G. | Kent, M. | Glass, E. N. | Agnew, D. | McDonough, S. | Miller, A. D.
An 11‐year‐old male castrated domestic shorthair cat presented with left central vestibular dysfunction. Magnetic resonance imaging of the brain revealed a large, extra‐parenchymal, strongly contrast‐enhancing mass at the level of the left cerebellopontine angle and compressing the cerebellum and brainstem. The mass was surgically excised via left rostral and sub‐tentorial craniectomies and histopathology revealed an epithelial neoplasm composed of anastomosing cords of neoplastic cells that contained large amounts of finely granular hypereosinophilic cytoplasm and round nuclei. The cytoplasmic granules were variably positive with periodic acid‐Schiff and modified Gomori trichrome. Immunohistochemical staining with anti‐cytokeratin AE1/AE3 was diffusely positive. Electron microscopy revealed neoplastic cells that were full of electron‐dense organelles consistent with mitochondria. This is the first case of a choroid plexus oncocytoma in the central nervous system of any domestic animal species and highlights the role of successful surgical intervention in extra‐parenchymal neoplasia in the central nervous system.
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