Ir-catalyzed asymmetric hydrogenation of β-keto esters with chiral ferrocenyl P,N,N-ligands
2017
Chen, Xiu-Shuai | Hou, Chuan-Jin | Qin, Chao | Liu, Hongzhu | Liu, Yan-Jun | Huang, De-Zhi | Hu, Xiang-Ping
The Ir-catalyzed asymmetric hydrogenation of β-keto esters with chiral ferrocenyl P,N,N-ligands has been developed. Under the optimized conditions, a wide range of β-keto esters were hydrogenated to afford the corresponding β-hydroxy esters in good to excellent enantioselectivities (up to 95% ee).
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书目信息
出版者
Multidisciplinary Digital Publishing Institute
其它主题
Enantioselectivity
语言
英语
类型
Journal Article; Text
2024-02-27
MODS