Enantio- and Diastereoselective Cyclopropanation of β,γ-Unsaturated α-Ketoester by a Chiral Phosphate/Indium(III) Complex
2017
Zhong, Xingren | Lv, Jian | Luo, Sanzhong
We report herein an enantioselective cyclopropanation of β,γ-unsaturated α-ketoesters with diazoesters by the complexes of InBr₃ and chiral calcium phosphate. The reaction proceeds via a Michael addition–cyclization pathway to afford highly functionalized chiral cyclopropanes with excellent enantioselectivities (up to >99% ee) as a single diastereoisomer.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
Elsevier Inc.
其它主题
Diastereoselectivity; Enantioselectivity; Diastereomers
语言
英语
类型
Journal Article; Text
2024-02-27
MODS