The sequence of human chromosome 21 and implications for research into Down syndrome
2000
Gardiner, Katheleen | Davisson, Muriel
The recent completion of the DNA sequence of human chromosome 21 has provided the first look at the 225 genes that are candidates for involvement in Down syndrome (trisomy 21). A broad functional classification of these genes, their expression data and evolutionary conservation, and comparison with the gene content of the major mouse models of Down syndrome, suggest how the chromosome sequence may help in understanding the complex Down syndrome phenotype.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
Springer-Verlag
其它主题
Trisomics; Down syndrome; Nucleotide sequences; Phenotype
语言
英语
许可
//data.crossref.org/schemas/AccessIndicators.xsd:license_ref>http://purl.org/eprint/accessRights/OpenAccess | //data.crossref.org/schemas/AccessIndicators.xsd:program>//data.crossref.org/schemas/AccessIndicators.xsd:license_ref> | //data.crossref.org/schemas/AccessIndicators.xsd:program>
类型
Journal Article; Text
2024-02-27
MODS