Uptake from Water, Internal Distribution and Bioaccumulation of Selenium in Scenedesmus obliquus, Unio mancus and Rattus norvegicus: Part A
2015
Polettini, Aldo-Eliano | Fortaner, Salvador | Farina, M. (Massimo) | Groppi, Flavia | Manenti, Simone | Libralato, Giovanni | Sabbioni, Enrico
The ⁷⁵Se internal bioavailability was investigated in microalgae, mussels and rats as biological experimental models. The ⁷⁵Se accumulation from freshwater to microalgae [Scenedesmus obliquus (Turpin) Kützing], from freshwater to mussels (Unio mancus Lamark) and, finally, per os to rats (Rattus norvegicus Berkenhout) was followed using ⁷⁵Se-labelled selenite looking at ⁷⁵Se uptake, retention, intracellular distribution and binding with cellular biocomplexes. After exposure to 10, 50 and 500 μg Se L⁻¹, the microalgae showed an inhibitory effect on population growth only at the highest concentration. Mussels exposed to 105 μg Se L⁻¹ showed an accumulation of the element with time in all tissues. Intracellularly, Se was present in all subcellular fractions, especially in the cytosol. Rats were treated via oral administration with 5 μg Se rat⁻¹. After 24 h, liver and kidney showed the highest Se concentration.
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