Lewis Acid Catalyzed Regiospecific Cross-Dehydrative Coupling Reaction of 2-Furylcarbinols with β-Keto Amides or 4-Hydroxycoumarins: A Route to Furyl Enols
2016
Miao, Maozhong | Luo, Yi | Li, Hongli | Xu, Xin | Chen, Zhengkai | Xu, Jianfeng | Ren, Hongjun
Lewis acid catalyzed directly dehydrative carbon–carbon bond formation reaction of 2-furylcarbinols with β-keto amides provides a straightforward method for regioselective synthesis of (Z)-furyl enols. Moreover, this Lewis acid catalyzed cross-coupling reaction can be extended to an interesting heterocyclic version featuring a functionalized 3-furyl-4-hydroxycoumarin synthesis.
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书目信息
Journal of organic chemistry
卷
81
期
12
页码
5228
- 5235
ISSN
1520-6904
出版者
American Chemical Society
其它主题
Cross-coupling reactions; Enols; Organic chemistry; Lewis acids; Chemical bonding; Regioselectivity; 4-hydroxycoumarins
语言
英语
类型
Journal Article; Text
2024-02-27
MODS