Iron and folate status before pregnancy and anemia during pregnancy
2003
Casanueva, E. | Pfeffer, F. | Drijanski, A. | Fernandez-Gaxiola, A.C. | Gutierrez-Valenzuela, V. | Rothenberg, S.J.
Background: A lack of information about the role that iron and folate stores (erythrocyte folate) play on the anemia incidence in pregnant women. Objective: To evaluate the predictive value of ferritin and erythrocyte folate before pregnancy in relationship to the incidence of anemia throughout pregnancy. Methods: Thirty-five non-anemic non-pregnant women were evaluated 1 or 2 months before the pregnancy. After becoming pregnant they were evaluated every 4 weeks starting in the 8th week of pregnancy until 1 month post-partum. Every evaluation included determination of hemoglobin, ferritin and erythrocyte folate. Results: When the women started gestation with an insufficient iron store (<20 micrograms/l), the trend was to present anemia at significantly earlier gestational ages, in such a way that at week 20 of gestation almost 60% of the women with an inadequate store had anemia and only 25% of the women with an adequate store had this condition. On the other hand, the pregestational erythrocyte folate did not predict anemia incidence. Conclusions: Pregestational ferritin concentration predicts value of incidence of anemia throughout pregnancy.
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