Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
2016
Phakhodee, Wong | Duangkamol, Chuthamat | Wiriya, Nittaya | Pattarawarapan, Mookda
A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph3P–I2 system in the presence of triethylamine as a desulfurization agent, monothioureas prepared in situ from the reaction of bis-nucleophiles with isothiocyanates underwent rapid cyclization to afford a variety of N-heterocyclic compounds in good to excellent yields under mild conditions.
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书目信息
出版者
John Wiley & Sons, Ltd
其它主题
2-aminobenzimidazole; Triethylamine; Isothiocyanates; Desulfurization; Aminooxazoline; Triphenylphosphine; Quinazolin-5-one; 2-aminobenzoxazole
语言
英语
注释
Pre-press version
类型
Journal Article; Text
2024-02-27
MODS