Association analyses of polymorphisms in porcine MYF5 and MYOD1 genes with carcass traits
2007
Liu, M. | Peng, J. | Xu, D.Q. | Zheng, R. | Li, F.E. | Li, J.L. | Zuo, B. | Lei, M.G. | Xiong, Y.Z. | Deng, C.Y. | Jiang, S.W.
The objective of this study was to assess the effect of polymorphisms of myogenic factor 5 (MYF5) and myogenic differentiation 1 (MYOD1) genes on carcass traits in pigs. PCR-RFLP was used to identify three and one SNP(s) from the MYF5 and the MYOD1 gene, respectively. Association analysis performed on the four polymorphisms in a series of three Large White Meishan F2 populations totalling near 400 pigs showed: (1) an MYF5 exon 1 Hsp92II polymorphism causing a Met-Leu substitution was significantly associated with fat meat percentage, shoulder fat thickness, thorax-waist fat thickness, average backfat thickness and carcass length to 1st rib (P < 0.05); (2) an MYF5 exon 2 MspI polymorphism and an intron 1 HaeIII polymorphism, which were completely linked, were significantly associated with thorax-waist fat thickness, 6-7th rib fat thickness and carcass length to 1st rib (P < 0.05); (3) an MYOD1 intron 1 DdeI polymorphism was significantly associated with carcass length to 1st rib.
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