A new oleanolic-type triterpene glycoside from Anchusa italica
2017
Chen, Kui-Kui | Xie, Zhou-Jian | Dai, Wei | Wang, Qi
A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β- d -glucopyranosyl-(1→2)-β- d -glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1) , together with five analogues, oleanazuroside 1 (2) , oleanazuroside 2 (3) , 24-hydroxytormentic acid ester glucoside (4) , 24-epi-pinfaensin (5) , and oleanolic acid 3-O-α- l -arabinoside (6) were isolated from the n -butyl alcohol extract of Anchusa italica . Their structures were determined spectroscopically and compared with previously reported spectral data. Compounds 3 – 4 and 6 were evaluated for their cytotoxic activities against five human cancer cell lines, but only compound 6 showed moderate cytotoxicity.
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