Schiff base interaction tuned mesoporous organosilica nanoplatforms with pH-responsive degradability for efficient anti-cancer drug delivery in vivo

LiuL. Liu and C. Kong contributed equally to this work., Lei; Kong, Chao; Huo, Meng; Liu, Chengyu; Peng, Liao; Zhao, Tian; Wei, Yan; Qian, Feng; Yuan, Jinying

Schiff base interaction tuned mesoporous organosilica nanoplatforms with pH-responsive degradability for efficient anti-cancer drug delivery in vivo

2018

Chemically incorporating Schiff base interactions into silicate frameworks endows the obtained mesoporous organosilica based drug carriers with ultrafast pH-responsive degradability and efficient anti-cancer drug release kinetics, resulting in enhanced cancer therapy.

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