Synthesis of substituted amido-isogranulatimide analogues as potential checkpoint1 kinase inhibitors

Salvetti, Béatrice; Lavrard, Hubert; Delfourne, Evelyne

Synthesis of substituted amido-isogranulatimide analogues as potential checkpoint1 kinase inhibitors

2014

Salvetti, Béatrice | Lavrard, Hubert | Delfourne, Evelyne

Two new regioisomeric series of substituted amido-isogranulatimide analogues were prepared in three steps from 2-imidazol-1-yl-1H-indol-5-ylamine. The experimental conditions of the last photocyclization step were determinant to obtain one or the other series.

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