Catalytic asymmetric total synthesis of (+)-artalbic acid
2016
Kobayashi, Toyoharu | Shioi, Ryuta | Ushie, Ai | Abe, H. (Hideki) | Ito, Hisanaka
The first total synthesis of (+)-artalbic acid has been accomplished using asymmetric allylation of an acetoacetate derivative with a phase-transfer catalyst. This synthetic work was completed in 12 steps from isopropyl acetoacetate with high stereocontrol. In addition, the absolute configuration of naturally occurring artalbic acid was determined to be 7S, 9S, and 10S.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
The Royal Society of Chemistry
其它主题
Allylation
语言
英语
类型
Journal Article; Text
2024-02-27
MODS