The Cell Lysis Activity of the Streptococcus agalactiae Bacteriophage B30 Endolysin Relies on the Cysteine, Histidine-Dependent Amidohydrolase/Peptidase Domain
2006
Donovan, David M. | Foster-Frey, Juli | Dong, Shengli | Rousseau, Geneviève M. | Moineau, Sylvain | Pritchard, David G.
The Streptococcus agalactiae bacteriophage B30 endolysin contains three domains: cysteine, histidine-dependent amidohydrolase/peptidase (CHAP), Acm glycosidase, and the SH3b cell wall binding domain. Truncations and point mutations indicated that the Acm domain requires the SH3b domain for activity, while the CHAP domain is responsible for nearly all the cell lysis activity.
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书目信息
出版者
Springer-Verlag
其它主题
Endopeptidases; Streptococcus phages; Peptidoglycan hydrolase; Cytolysis; B30 endolysin; Amino acid sequence; Lysogeny; Histidine-dependent amidohydrolase/peptidase; Animal diseases (bacterial); Drug effects; Amidohydrolases
语言
英语
注释
Includes references
2019-12-06
许可
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类型
Journal Article; Text
2024-02-28
MODS