First case report of pulmonary blastoma in a dog in Tunisia: A comparative study with human
2017
Smadhi, H. | Rejeb, A. | Amel, H. | Blouza, R. | Ben Maitigue, H. | Semin, M.O. | Delverdier, M.
Pulmonary blastoma (PB) is a rare biphasic tumor formed by mixed epithelial-and-mesenchymal elements. In this trial, we report a first case in Tunisia of a dog with multiple pulmonary masses characteristics of PB. At postmortem, the gross lesions were described as multiple white circumscribed masses throughout the lungs. Histological analysis of lungs shows that the tumor contains dual population of mesenchymal and epithelial neoplastic cells. Mesenchymal elements were immunoreactive for vimentin and neuron specific enolase. Epithelial cells lining tubules lumina were non-ciliated and cuboidal with central round nuclei showing strong immunoreactivity for cytokeratin. This study reveals that clinical, histological and immunohistochemical findings of PB in dog are similar to those in human PB.
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