Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
2019
Aksenov, Alexander V. | Khamraev, Vladislav | Aksenov, Nicolai A. | Kirilov, Nikita K. | Domenyuk, Dmitriy A. | Zelensky, Vladimir A. | Rubin, Michael
A novel methodology for general and chemoselective preparation of non-symmetric 1,3,4-oxadiazoles is developed. This unusual reaction proceeds via polyphosphoric acid-assisted activation of nitroalkanes towards nucleophilic attack with acylhydrazides.
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出版者
The Royal Society of Chemistry
其它主题
Chemoselectivity; Nitroalkanes; Lewis acids; Lewis bases
语言
英语
类型
Journal Article; Text
2024-02-28
MODS