Effects of structured triacylglycerols containing stearic, acetic, and propionic acids on the intestinal microflora of rats
1994
Scheinbach, S. | Hayes, J.R. | Carman, R.J. | Zhou, D. | Van Tassell, R.L. | Wilkins, T.D.
The structured triacylglycerols SALATRIM 23CA lot A014 and SALATRIM 32CA lot A015 exhibit lower caloric availability than corn oil. Acetate and stearate predominate in SALATRIM 23CA lot A014 and propionate and stearate in SALATRIM 32CA lot A015. Rats were exposed for 13 weeks to rodent chow or 10% (w/w) SALATRIM 23CA lot A014, SALATRIM 32CA lot A015, or corn oil. Cecal contents were examined for changes in five variables associated with intestinal bacterial activity: (1) bacterial morphotypes, (2) cecal pH, (3) conversion of primary to secondary bile acids, (4) conversion of primary to secondary phytosterols, and (5) conversion of cholesterol to coprostanol. Fusiform rods (diet-sensitive bacteria) were not detectably altered by the SALATRIM fats. No major pH differences were detected. No biologically significant differences were seen in secondary bile acid levels as a percent of total, nor did the ratios of cholesterol to coprostanol vary significantly, indicating that bacterial conversions were unaffected. Whereas all four secondary phytosterols increased with corn oil, only one (24 alpha-methylcoprostanol) increased with SALATRIM 32CA lot A015. SALATRIM fats had less effect, if any, on the intestinal microflora of rats than corn oil.
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