Suppression of Francisella tularensis growth in the rat by co-infection with F. novicida
1997
Cowley, S.C. | Myltseva, S.V. | Nano, F.E.
We have previously shown that when cultured in vitro, peritoneal rat macrophages infected with Francisella novicida spontaneously release nitric oxide in sufficient quantities to inhibit bacterial growth. However, it is not known whether F. novicida can have a similar antimicrobial effect in vivo. Here we show that a co-infection of F. novicida with Francisella tularensis can suppress the number of F. tularensis cells in rat spleens by as much as 100-fold.
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书目信息
出版者
Multidisciplinary Digital Publishing Institute
其它主题
Anti-infective properties; Mixed infection; Microbial growth; Inbred lew; Female; Francisella tularensis subsp. novicida; Growth & development
语言
英语
类型
Journal Article; Text
2024-02-28
MODS