Suzuki–Miyaura cross-coupling of alkenyl tosylates with alkenyl MIDA boronates

Lüthy, Monique; Taylor, Richard J.K.

Suzuki–Miyaura cross-coupling of alkenyl tosylates with alkenyl MIDA boronates

2012

Lüthy, Monique | Taylor, Richard J.K.

A practical procedure for the palladium-catalysed Suzuki–Miyaura coupling of various alkenyl tosylates with alkenyl MIDA boronates has been developed. Commercially available trans-bromo[N-succinimidyl-bis(triphenylphosphine)]palladium(II) [Pd(PPh₃)₂NBS] is an effective catalyst under the slow release conditions of MIDA boronates; with less activated alkenyl tosylates addition of the cheap, air-stable tricyclohexylphosphine tetrafluoroborate enhances reactivity.

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