The relationship among dietary undetermined anion, acid-base balance, and nutrient metabolism in swine
1997
Patience, J.F. | Chaplin, R.K.
Dietary undetermined, anion (dUA) reflects, in part, the net acid load contributed by the diet. Although dUA is known to influence performance and nutrient metabolism of swine, a lack of knowledge impairs its application to diet formulation. This study was undertaken to separate the effects of dUA from the individual electrolytes that constitute its calculation. Eighteen 35-kg pigs were fitted with indwelling venous catheters and fed one of three barley and soybean meal-based diets: a control diet (C), an acidogenic diet containing calcium chloride (A), or a compensated acidogenic et containing alkaline salts of sodium and potassium, as well as calcium chloride (CA). Compared with diet C, diet A lowered (P < .05) blood pH, bicarbonate, and base excess and increased (P < .05) urinary ammonium, titratable acid (TA), and net acid excretion (NAE). Diet CA returned blood acid-base values to normal and reduced urinary ammonium, TA, and NAE relative to diet A. Total nitrogen balance was unaffected by diet. Diet CA increased (P < .05) water intake and urine output. Diet A, but not CA, increased (P < .05) serum ionized Ca and Cl. Apparent Ca and S digestibility and retention were reduced by diet A, but not by CA. Sodium retention was enhanced (P < .05) by diets A and CA; potassium retention was impaired (P < .05) by CA. Dietary UA altered systemic and renal acid-base balance in pigs. Mineral, but not nitrogen, metabolism was affected by both dUA and specific ion effects.
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