A new benzofuran glycoside from the fruit of Clausena lansium
2022
Ao, Huiting | Jia, Xuchao | Dong, Lihong | Zhang, Ruifen | Liu, Lei | Huang, Fei | Wang, Lixia | Zhang, Mingwei
In this work, we isolated a new benzofuran glycoside, 6-β-d-glucosyl-6,7-dihydroxy-5-benzofuranpropanoic acid methyl ester (1), together with six known compounds (2–7) from the fruits of Clausena lansium (Lour.) Skeels. Extensive spectroscopic methods were employed to elucidate their structures. Herein, compounds 2, 3, 5 and 6 were reported from Clausena lansium (Lour.) Skeels for the first time. Moreover, compounds 1, 2, 4 and 6 showed comparable 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging activity to l-ascorbic acid, and compound 4 also exhibited potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing antioxidant power (FRAP). All of the compounds showed oxygen radical absorbance capacity (ORAC) values ranging from 0.3 to 3.6 μmol trolex equivalent/μmol. In addition, compounds 3 and 5 also demonstrated good α-amylase inhibitory activity.
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