P2 receptors and immunity
2012
Rayah, Amel | Kanellopoulos, Jean M. | Di Virgilio, Francesco
Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on multiple immune cell responses such as T lymphocyte proliferation, chemotaxis, cytokine release, phagocytosis, Ag presentation and cytotoxicity. This makes P2 receptors an attractive target for the therapy of immuno-mediated disease and cancer.
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书目信息
Microbes and Infection
卷
14
期
14
页码
1254
- 1262
ISSN
1286-4579
出版者
Elsevier B.V.
其它主题
Therapeutics
语言
英语
类型
Journal Article; Text
2024-02-28
MODS