An Individual-Centered Framework For Unravelling Genotype-Phenotype Interactions

Baguette, Michel; Legrand, Delphine; Stevens, Virginie M.

An Individual-Centered Framework For Unravelling Genotype-Phenotype Interactions

2015

Baguette, Michel | Legrand, Delphine | Stevens, Virginie M.

A new framework in which the multiple levels of molecular variations contribute to phenotypic variations in a complex, nonlinear and interactive way, challenges the hierarchical nature of the relationships between the genotypic and phenotypic spaces. This individual-centered framework provides new insights on the evolutionary mechanisms involved in the production of phenotypes. We propose to move this research agenda forward by combining selection experiments and functional genetics.

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