Dermatophilosis (lumpy wool) in sheep: a review of pathogenesis, aetiology, resistance and vaccines
2021
Tellam, Ross L. | Vuocolo, Tony | Denman, Stuart | Ingham, Aaron | Wijffels, Gene | James, Peter J. | Colditz, Ian G.
Lumpy wool (dermatophilosis) develops following prolonged wetting of sheep when bacterial proliferation in wool and on skin induce an exudative dermatitis, causing a superficial skin lesion and damage to wool follicles and fibres. The incidence of dermatophilosis is strongly dependent on wet and warm weather and, hence, infection is sporadic. While older animals are less at risk than are lambs, it is unclear whether this reflects naturally acquired immune resistance or the maturation of skin and wool fibres. Dermatophilosis directly causes wool production losses and it also is a risk factor for blowfly strike, which has a substantial economic impact and increasing challenges associated with current control procedures. This review assessed research on the bacterial causes of lumpy wool, the characteristics of the resulting immune defence reactions in sheep, current control strategies, and limitations of previous attempts to control lumpy wool by sheep vaccination.
显示更多 [+] 显示较少 [-]