Immobilization-free screening of aptamers assisted by graphene oxide

Park, Jee-Woong; Tatavarty, Rameshwar; Kim, Dae Woo; Jung, Hee-Tae; Gu, Man Bock

Immobilization-free screening of aptamers assisted by graphene oxide

2012

Park, Jee-Woong | Tatavarty, Rameshwar | Kim, Dae Woo | Jung, Hee-Tae | Gu, Man Bock

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

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