Bioavailability of two ibuprofen oral paste formulations in fed or nonfed ponies
1992
Vandenbossche, G.M.R. | Bouckaert, S. | Muynck, C. de | Mommens, G. | Zeveren, A. van | Remon, J.P.
The bioavailability and pharmacokinetics of ibuprofen, a nonsteroidal antiinflammatory drug, was studied in healthy Shetland ponies. Ibuprofen was administered IV, as a suspension, and as a solid solution oral paste to ponies from which food was withheld. The suspension paste was also administered to ponies that received hay and water ad libitum. Both formulations had an absolute bioavailability of about 80%. Bioavailability was not influenced by feeding.
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书目信息
American journal of veterinary research
卷
53
期
4
页码
528
- 531
ISSN
0002-9645
出版者
Elsevier Ltd
其它主题
Anti-inflammatory agents; Administration & dosage; Drug formulations; Oral; Biological availability; Ibuprofen; Female; Ointments; Male; Half-life
语言
英语
类型
Text; Journal Article
2024-02-28
MODS
