Antimicrobial tests of soap based on ethanolic extract of leaves of Morinda morindoides (Morinda, Rubiaceae) on in vitro growth of germs involved in skin infections | Essais antimicrobiens d’un savon à base d’extrait éthanolique des feuilles de Morinda morindoides (Morinda, Rubiaceae) sur la croissance in vitro de germes impliqués dans les infections cutanées
2017
Touré, A. | Ouattara, K. | Ouattara, A. | Coulibaly, A.
The objective of this study is to develop a soap based on the ethanolic extract of the leaves of Morinda morindoides and to evaluate its antimicrobial activity on the in vitro growth of two bacteria (Staphylococcus aureus and Pseudomonas aeruginosa) and four fungi (Candida albicans, Candida tropicalis, Trichophyton rubrum, and Trichophyton mentagrophytes) involved in skin infections. The ethanolic extract of Morinda morindoides was used as an antimicrobial agent in the manufacture of an anti-infectious soap coded “S2” using a cold process. The antifungal tests of soap with ethanolic extract of Morinda morindoides (S2) and control soap (S0) were carried out using the broth dilution method by incorporation of test soap into Sabouraud agar. The antibacterial parameters of soaps S2 and S0 were determined by incorporation into Mueller-Hinton agar and testing in liquid medium. Soap S2 expressed an effective antimicrobial activity compared to soap S0 with a MIC (Minimum Inhibitory Concentration) of 31.25 mg/ml against tested microbial germs. We conclude that incorporation of 10% of ethanolic extract of Morinda morindoides in the formulation of an anti-infectious soap does not alter its antimicrobial properties. In view of the effectiveness of soap S2 on microbial germs involved in skin infections, its production on an industrial scale will constitute a real hope in the fight against skin diseases, which are very widespread in Côte-d’Ivoire.
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