Synthesis of 3-spiropyrrolidine-3-spirooxindoles from Baylis–Hillman adducts of chromone with azomethine ylides via [3+2] cycloaddition reaction
2013
Yuvaraj, Panneerselvam | Reddy, Boreddy S.R.
3-Spiropyrrolidine-oxindole unit is a privileged heterocyclic motif forming the core of a large family of alkaloid natural products with strong bioactivity profile and interesting structural properties. A novel regioselective synthesis of functionalized 3-spiropyrrolidine-3-spirooxindoles from 4-oxo-4H-chromone derivatives was accomplished by the [3+2] cycloaddition of azomethineylides with Baylis–Hillman adducts.
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书目信息
出版者
Elsevier Ltd
其它主题
Spiro [pyrrolidine/oxindole]; [3+2] cycloaddition; Azomethineylides; Regioselectivity; Baylis–hillman adduct
语言
英语
类型
Journal Article; Text
2024-02-28
MODS