RGD-decorated conjugated polymer particles as fluorescent biomedical probes prepared by Sonogashira dispersion polymerization
2015
Anwar, Naveed | Rix, Anne | Lederle, Wiltrud | Kuehne, Alexander J. C.
Here, we present a facile one-step Sonogashira dispersion polymerization affording monodisperse conjugated polymer particles bearing accessible acetylene moieties on the surface. These acetylene groups are easily functionalized with biological recognition motifs using thiol–yne click chemistry. The resulting functional particles are applied as fluorescent probes for imaging of activated endothelial cells, which take up the particles via receptor mediated endocytosis.
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书目信息
出版者
The Royal Society of Chemistry
其它主题
Moieties; Endothelial cells; Fluorescent dyes
语言
英语
类型
Journal Article; Text
2024-02-28
MODS