Evaluation of acepromazine, dexmedetomidine and xylazine as prenaesthetics to propofol-halothane anaesthesia in dogs
2016
Yadav, S. | Malik, V. | Rajput, A. | Pandey, R.P.
The objective of this study was to compare the suitability and efficacy of three preanaesthetic combinations administered intramuscularly viz., glycopyrrolate (0.01 mg/kg) + xylazine (0.5 mg/kg) + butorphanol (0.2 mg/kg) in group I; glycopyrrolate (0.01 mg/kg) + dexmedetomidine (5 mcg/kg) + butorphanol (0.2 mg/kg) in group II; glycopyrrolate (0.01 mg/kg) + acepromazine (0.05 mg/kg) + butorphanol (0.2 mg/kg) in group III for propofol-halothane anaesthesia in clinical cases of dogs. The preanaesthetic combinations in all three groups produced mild to moderate sedation in the animals and decreased the requirement of propofol for anaesthetic induction. Clinicophysiological parameters in animals of all groups altered within physiological limit and nearly normalised at complete recovery. Preanaesthetic combination of glycopyrrolate (0.01 mg/kg) + dexmedetomidine (5 mcg/kg) + butorphanol (0.2 mg/kg) was found to be the best among three combinations in terms of the quality of sedation, early onset of sedation and dose sparing effect on induction and maintenance agents.
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