The finite polygenic mixed model: an alternative formulation for the mixed model of inheritance
1994
Fernando, R.L. | Stricker, C. | Elston, R.C.
This paper presents a mixed model of inheritance with a finite number of polygenic loci. This model leads to a likelihood that can be calculated using efficient algorithms developed for oligogenic models. For comparison, likelihood profiles were obtained for the finite polygenic mixed model, the usual mixed model, with exact and approximate calculations, and for a class D regressive model. The profiles for the finite polygenic mixed model were closest to the profiles for the usual mixed model with exact calculations.
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书目信息
Theoretical and applied genetics
卷
88
期
5
页码
573
- 580
ISSN
0040-5752
其它主题
Polygenic loci; Genetic models; Mixed model inheritance; Polygenic inheritance; Maximum likelihood; Inheritance (genetics)
语言
英语
注释
2019-12-05
类型
Journal Article; Text
2024-02-28
MODS