Biological activity of 6-pentyl-2H-pyran-2-one and its analogs

Parker, S.R.; Cutler, H.G.; Jacyno, J.M.; Hill, R.A.

Biological activity of 6-pentyl-2H-pyran-2-one and its analogs

1997

Parker, S.R. | Cutler, H.G. | Jacyno, J.M. | Hill, R.A.

The in vitro biological activities (antifungal, phytotoxic) for a group of fungal metabolites structurally related to 6-pentyl-2H-pyran-2-one have been determined. Six compounds were tested and showed a degree of phytotoxicity in one or more of the assays employed. From among the analogs tested, (R)-5,6-dihydro-6-pentyl-2H-pyran-2-one has been identified as the most active against Penicillium species.

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