The Inner Compass of Spindle Positioning and Orientation

Fong, Chii Shyang; Tsou, Meng-Fu Bryan

The Inner Compass of Spindle Positioning and Orientation

2012

Fong, Chii Shyang | Tsou, Meng-Fu Bryan

Polarized cortical cues are known to guide spindle movements to dictate division axis and cleavage site during asymmetric cell division. In a recent issue of Nature Cell Biology, Kiyomitsu and Cheeseman (2012) report two novel spindle-intrinsic signals that regulate spindle orientation and position in symmetrically dividing human cells.

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