Surfaces with instant and persistent antimicrobial efficacy against bacteria and SARS-CoV-2
2022
Dhyani, Abhishek | Repetto, Taylor | Bartikofsky, Dylan | Mirabelli, Carmen | Gao, Zhihe | Snyder, Sarah A. | Snyder, Catherine | Mehta, Geeta | Wobus, Christiane E. | VanEpps, J Scott | Tuteja, Anish
Surfaces contaminated with bacteria and viruses contribute to the transmission of infectious diseases and pose a significant threat to global public health. Modern day disinfection either relies on fast-acting (>3-log reduction within a few minutes), yet impermanent, liquid-, vapor-, or radiation-based disinfection techniques, or long-lasting, but slower-acting, passive antimicrobial surfaces based on heavy metal surfaces, or metallic nanoparticles. There is currently no surface that provides instant and persistent antimicrobial efficacy against a broad spectrum of bacteria and viruses. In this work, we describe a class of extremely durable antimicrobial surfaces incorporating different plant secondary metabolites that are capable of rapid disinfection (>4-log reduction) of current and emerging pathogens within minutes, while maintaining persistent efficacy over several months and under significant environmental duress. We also show that these surfaces can be readily applied onto a variety of desired substrates or devices via simple application techniques such as spray, flow, or brush coating.
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