“One-Pot” Reductive Lactone Alkylation Provides a Concise Asymmetric Synthesis of Chiral Isoprenoid Targets
2013
Cao, Jia | Perlmutter, Patrick
An efficient method, based on nucleophilic addition to lactones followed by modified in situ Clemmensen reduction, provides a short synthetic route to chiral isoprenoid targets. The efficacy of this method has been exemplified through the synthesis of several targets including the commercial fragrance Rosaphen, the side chain of Zaragozic acid C, the cotton leaf sex pheromone, and the side chains of vitamin E.
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书目信息
Organic letters
卷
15
期
17
页码
4327
- 4329
ISSN
1523-7052
出版者
American Chemical Society
其它主题
Odors; Alkylation; Lewis bases
语言
英语
类型
Journal Article; Text
2024-02-28
MODS