Isolation and characterization of the canine NKX2-5 gene
2006
Hyun, C. | Lavulo, L. | O'Leary, C. | Kim, J-T.
We report the first isolation and characterization of the canine NKX2-5 gene. This canine homologue has high homology in genomic structure and functional domains to other NKX2-5 across a number of different species. Given the critical role of NKX2-5 in cardiac morphogenesis as seen in human and mouse studies of congenital heart defects, the availability of the canine NKX2-5 provides a good starting point for identifying mutations that may be responsible for certain forms of canine congenital heart defects.
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书目信息
出版者
Blackwell Publishing Ltd
其它主题
Molecular sequence data; Animal diseases (physiological); Sequence homology; Amino acid; Homeodomain proteins; Dna primers; Female; Animal development; Amino acid sequence; Base sequence; Gene order; Nucleotide sequences; Animal breeding and genetics; Molecular sequence data
语言
英语
注释
Includes references
类型
Journal Article; Text
2024-02-28
MODS