Sortase A-catalyzed peptide cyclization for the synthesis of macrocyclic peptides and glycopeptides
2011
Wu, Zhimeng | Guo, Xueqing | Guo, Zhongwu
A chemoenzymatic method was developed for the synthesis of macrocyclic peptides and glycopeptides. Sortase A was found to mediate either head to tail cyclization or oligomerization and then head to tail cyclization of peptides and glycopeptides, depending on the peptide length, to produce 15-mer or higher cyclic peptides and glycopeptides.
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书目信息
Chemical communications
卷
47
期
32
页码
9218
- 9220
ISSN
1364-548X
出版者
The Royal Society of Chemistry
其它主题
Chemical communication; Oligomerization; Sortase a; Cyclic peptides
语言
英语
许可
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类型
Journal Article; Text
2024-02-28
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