Rh₂(OAc)₄ catalyzed substrate selective [4+2]/[2+2] cycloaddition of acylketenes: a highly chemo- and regioselective synthesis of spiro(oxindolyl)oxazinones and β-lactams

Subba Reddy, B.V.; Karthik, Govindaraju; Rajasekaran, Tamilselvan; Antony, A.; Sridhar, B.

Rh₂(OAc)₄ catalyzed substrate selective [4+2]/[2+2] cycloaddition of acylketenes: a highly chemo- and regioselective synthesis of spiro(oxindolyl)oxazinones and β-lactams

2012

Subba Reddy, B.V. | Karthik, Govindaraju | Rajasekaran, Tamilselvan | Antony, A. (Aneesh) | Sridhar, B.

A rhodium(II) catalyzed [4+2]/[2+2] cycloaddition reaction of N-protected isatin-3-arylimine with acylketene derived from α-diazocarbonyl compounds has been achieved for the first time for the preparation of a novel class of spiro(oxindolyl)oxazinone and spiro(oxindolyl)-β-lactam derivatives.

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