Characterization of monascidin A from Monascus as citrinin
1995
Blanc, P.J. | Laussac, J.P. | Le Bars, J. | Le Bars, P. | Loret, M.O. | Pareilleux, A. | Prome, D. | Prome, J.C. | Santerre, A.L. | Goma, G.
Following our investigations on red pigments and monascidin co-production by Monascus species, the antibiotic called monascidin A was characterized as citrinin. Evidence was given by qualitative methods, mass spectra and NMR. Citrinin, a nephrotoxic agent was produced both by Monascus purpureus and Monascus ruber, either in submerged culture of concentrations of 270 and 340 mg/l, respectively, or in solid state culture of concentration of 100 and 300 mg/kg dried matter, respectively. Since citrinin is a toxic product, it is essential that the production of red pigments as food additives from Monascus spp. avoid the occurrence of citrinin.
显示更多 [+] 显示较少 [-]