Preferential decay of passively acquired immunoglobulins recognizing shared gram-negative core antigens in neonatal swine

Tyler, J.W.; Cullor, J.S.; Douglas, V.L.; Smith, W.L.; Parker, K.M.

Preferential decay of passively acquired immunoglobulins recognizing shared gram-negative core antigens in neonatal swine

1989

Tyler, J.W. | Cullor, J.S. | Douglas, V.L. | Smith, W.L. | Parker, K.M.

Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured by use of a direct ELISA on blood obtained from 10 neonatal swine. An R-mutant Escherichia coli (strain J5) was used as a plate antigen. Total serum IgG was measured by use of radial immunodiffusion. Half-lives of core antigen-specific IgG (6.81 days) and total serum IgG (14.85 days) were dramatically different (P less than 0.01).

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