Growth, lipid metabolism and pathology of two strains of rats fed high fat diets
1979
Kramer, J.K.G. | Hulan, H.W. | Trenholm, H.L. | Corner, A.H.
Extract: Sprague-Dawley (SD) and Chester Beatty (CB) young, male rats were fed diets which contained 20 percent by weight of either corn, LEAR (low erucic acid) or HEAR (high erucic acid rapeseed) oils for a period of up to 16 weeks. A significantly lower incidence of focal myocardial necrosis was observed in CB rats than in SD rats. In SD rats a higher incidence was observed in the groups fed rapeseed oils. In both strains the growth rates of rats fed LEAR and corn oils were similar; growth rates with HEAR oil diets were much lower than the other oils. There was no evidence to indicate that differences in heart lesion response between the two rat strains could be related to cardiac triglycerides, free fatty acids or phospholipids.
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