Distribution of genes and recombination in wheat and other eukaryotes
2004
Sidhu, D. | Gill, K.S.
The genome sizes of eukaryotes may differ as much as 10,400-fold. A part of these differences may be attributed to polyploidy, and increase in gene number and size. Most of the genome size disparity is due to non-transcribed repeated DNA including retrotransposons and pseudogenes. Only a small fraction of the larger genomes such as those of many crop plants, contain genes. Genes are distributed unevenly along the chromosomes, often organized in clusters of varying sizes and gene-densities (gene-rich regions). The regions corresponding to gene-clusters in smaller genome plants such as rice may be divided into many mini gene-clusters in the related larger genomes. The range of gene-density within the mini2019; gene-clusters is about the same among plants with varying genome sizes. Recombination per chromosome is similar among eukaryotes, and thus is considerably independent of DNA content and chromosome size. Relatively little recombination occurs outside the gene-rich regions. Recombination varies dramatically among various gene regions, and is highly uneven within gene regions as well. Consequently, a significant number of genes may be inaccessible to recombination-based manipulations such as map-based cloning.
显示更多 [+] 显示较少 [-]