Malettinin A: a new antifungal tropolone from an unidentified fungal colonist of Hypoxylon stromata (NRRL 29110)
2003
Angawi, Rihab F. | Swenson, Dale C. | Gloer, James B. | Wicklow, Donald T.
Malettinin A (1) has been isolated from cultures of an unidentified fungus encountered as a colonist of Hypoxylon stromata. The structure of 1 was proposed by analysis of NMR and MS data, and confirmed by X-ray diffraction analysis of a methanol adduct. Malettinin A shows significant activity in assays against Aspergillus flavus. Malettinin A (1) has been isolated from cultures of an unidentified fungus encountered as a colonist of Hypoxylon stromata. The structure of 1 was proposed by analysis of NMR and MS data, and confirmed by X-ray diffraction analysis of a methanol adduct. Malettinin A shows significant activity in assays against Aspergillus flavus.
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