Chemical Composition and Bioactivity of Acantholippia seriphioides Essential Oils from Patagonia
2011
Mazzuca, Marcia | Berezosky, Javier | Cerdá, Roberto C. | Arce, María Elena | Baren, Catalina van | Di Leo Lira, Paola | Bandoni, Arnaldo
The aerial parts of Acantholippia seriphioides (A. Gray) Mold. were collected from three sites in the neighborhood of Comodoro Rivadavia, in Patagonia (Astra, Saavedra and Rada Tilly), and their essential oils were analyzed by GC-FID/MS. Results obtained by the analysis indicated chemovariability in the oils from these sites when matched with other sites. Monoterpene hydrocarbons (92.6-95.1%) were the main group of constituents in all populations, mainly thymol (33.7-38.5%) p-cymene (26.5-35.3%) and g-terpinene (8.3-12.7%). Essential oils were submitted to biological assays in order to assess their general toxic activity on Artemia salina, and the inhibition effects in the germination and seedling growth of Lactuca sativa. Saavedra sample, associated with greater limonene, carvone, carvacrol and p-cymene contents, was the most active to the A. salina test (LD50 = 23,08 micrograms/mL-1). Astra sample, associated to a greater relative proportion of g-terpinene, thymol methyl ether and neral, was the most active to the germination and seedling growth test (IC50=1.86 micrograms/mL-1). Saavedra sample also showed high activity (IC50= 37.53 micrograms/mL-1). The bioactivities were not proportional to the content of present active monoterpenes.
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