Discovery of Plant Growth Stimulants by C–H Arylation of 2-Azahypoxanthine
2018
Kitano, Hiroyuki | Choi, Jae-Hoon | Ueda, Ayaka | Ito, Hideto | Hagihara, Shinya | Kan, Toshiyuki | Kawagishi, Hirokazu | Itami, Kenichiro
A series of new AHX derivatives were synthesized by Pd-catalyzed C–H arylation. Their rice-growth-promoting activity was evaluated in vivo. Among the synthesized compounds, C8 phenyl-substituted AHX showed remarkable growth-promoting activity on rice. The present study shows the power and significant opportunity of C–H functionalization chemistry to rapidly transform biologically active natural products into more active compounds.
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书目信息
出版者
American Chemical Society
其它主题
Carbon-hydrogen bond activation; Active ingredients; Arylation
语言
英语
类型
Journal Article; Text
2024-02-28
MODS