Benzeneselenol-modified gold nanoclusters for cancer therapy
2020
Wang, Le | Zheng, Wenfu | Jiang, Xingyu
We report benzeneselenol-modified gold nanoclusters (Se_Au NCs) that have significant anticancer activity by inducing autophagy and disassembly of F-actin in cancer cells. Upon treatment of different tumor models on mice, it has been found that Se_Au NCs exhibit excellent antitumor efficacy, high stability, and extremely low toxicity, which are the requirements for an ideal antineoplastic drug. Our study is a successful attempt in exploring novel anticancer agents with high biosafety.
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书目信息
Chemical communications
卷
56
期
49
页码
6664
- 6667
ISSN
1364-548X
出版者
The Royal Society of Chemistry
其它主题
Autophagy; Nanogold; Antineoplastic activity; Cancer therapy; Neoplasm cells
语言
英语
类型
Journal Article; Text
2024-02-28
MODS