Intersection point method (IPM): theoretical basis and application to spectrophotometric analyses

Cerdán-Vidal, A.; Maurí-Aucejo, A. R.; Llobat-Estellés, M.; Pascual-Martí, M. C.

Intersection point method (IPM): theoretical basis and application to spectrophotometric analyses

1997

Cerdán-Vidal, A. | Maurí-Aucejo, A. R. | Llobat-Estellés, M. | Pascual-Martí, M. C.

The Intersection Point Method (IPM) is a new method for the determination of an analyte in the presence of several unknown interferences. The method is based on the Apparent Content Curves (ACC) from derivative signals. To test the proposed procedure an analysis of mixtures of indicators with strong spectral overlapping was carried out. Results obtained agree with the theoretical values. Besides, the determination of caffeine in several pharmaceuticals by IPM provides good results.

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