Low mannose-binding lectin (MBL) levels in neonates with pneumonia and sepsis
2007
Frakking, F.N.J. | Brouwer, N. | van Eijkelenburg, N.K.A. | Merkus, M.P. | Kuijpers, T.W. | Offringa, M. | Dolman, K.M.
We investigated whether deficiency of mannose-binding lectin (MBL), a component of innate immunity, is associated with neonatal pneumonia and sepsis during the first 72 h, i.e. early onset, and during the first month after birth. In 88 neonatal intensive care patients (71 premature), MBL2 genotype and MBL plasma levels at birth were determined prospectively by Taqman analysis and enzyme-linked immunosorbent assay, respectively. Thirty-five neonates (40%) had low, i.e.
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书目信息
出版者
Oxford, UK : Blackwell Publishing Ltd
其它主题
Sepsis; Sepsis; Deficiency; Bacterial; Premature; Complement; Obstetric; Delivery; Female; Mannose-binding lectin; Newborn; Premature; Gestational age; Genotype; Critical care; Male; Mannose-binding lectin; Neonates; Disease susceptibility
语言
英语
类型
Journal Article; Text
2024-02-28
MODS