Late-Stage Deoxyfluorination of Alcohols with PhenoFluor
2013
Sladojevich, Filippo | Arlow, Sophie I. | Tang, Pingping | Ritter, Tobias
An operationally simple protocol for the selective deoxyfluorination of structurally complex alcohols is presented. Several fluorinated derivatives of natural products and pharmaceuticals have been prepared to showcase the potential of the method for late-stage diversification and its functional group compatibility. A series of simple guidelines for predicting the selectivity in substrates with multiple alcohols is given.
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书目信息
出版者
American Chemical Society
语言
英语
许可
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类型
Journal Article; Text
2024-02-28
MODS