Divergent Conversion of N-Acyl-isoxazol-5(2H)-ones to Oxazoles and 1,3-Oxazin-6-ones Using Photoredox Catalysis

Mei, Mingjing; Anand, Devireddy; Zhou, Lei

Divergent Conversion of N-Acyl-isoxazol-5(2H)-ones to Oxazoles and 1,3-Oxazin-6-ones Using Photoredox Catalysis

2019

Mei, Mingjing | Anand, Devireddy | Zhou, Lei

The fragmentation of N-acyl-isoxazol-5-ones using visible light photoredox catalysis has been disclosed. The catalyst-controlled divergent mechanisms, namely the oxidative and reductive quenching catalytic cycle, are utilized. Various oxazoles and 1,3-oxazin-6-ones are selectively obtained from the same isoxazol-5-one skeleton under mild conditions.

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